A database of 305 pairs of mammalian virus-host receptor interaction, which included 138 unique viral species/sub-species and 144 receptors, are curating by Peng Lab. We analyzed the structural, functional, evolutionary and tissue-specific expression characteristics of mammalian virus receptors, and provide some new insights into viral receptor selection and identify viral receptors (see more details).

Family Family TaxID Virus Virus TaxID Host Host TaxID UniprotKB AC Refseq protein Gene name Gene GeneID Pubmed
Hepadnaviridae 10404 Hepatitis B virus 10407 Pan troglodytes (Chimpanzee) 9598H2Q8J0 XP_510035.2solute carrier family 10 member 1SLC10A1453001 PMID: 26523264   
Hepadnaviridae 10404 Hepatitis B virus 10407 Homo sapiens (Human) 9606P78333NP_004457.1glypican 5GPC52262 PMID: 26315853 30145242 30541833   
Hepadnaviridae 10404 Hepatitis B virus 10407 Homo sapiens (Human) 9606Q14973 NP_003040.1solute carrier family 10 member 1SLC10A16554 PMID: 26523264 23150796   
Retroviridae 11632 Feline immunodeficiency virus 11673 Felis catus (Cat) 9685P56498NP_001009826.1C-X-C motif chemokine receptor 4CXCR4493676 PMID: 10196258   
Retroviridae 11632 Feline immunodeficiency virus 11673 Felis catus (Cat) 9685Q75SV8 NP_001009200.1TNF receptor superfamily member 4TNFRSF4493665 PMID: 14976315   
Retroviridae 11632 Human immunodeficiency virus 1 11676 Homo sapiens (Human) 9606P01730NP_000607.1CD4 moleculeCD4920 PMID: 17346169   
Retroviridae 11632 Human immunodeficiency virus 1 11676 Homo sapiens (Human) 9606P51681 NP_000570.1C-C motif chemokine receptor 5 (gene/pseudogene)CCR51234 PMID: 9632396 21763489   
Retroviridae 11632 Human immunodeficiency virus 1 11676 Homo sapiens (Human) 9606P61073NP_001008540.1C-X-C motif chemokine receptor 4CXCR47852 PMID: 9427609 10756055   
Retroviridae 11632 Human immunodeficiency virus 1 11676 Homo sapiens (Human) 9606Q9H2X3 NP_001138377.1C-type lectin domain family 4 member MCLEC4M10332 PMID: 21277928 12502850   
Retroviridae 11632 Human immunodeficiency virus 1 11676 Homo sapiens (Human) 9606Q9NNX6NP_001138365.1CD209 moleculeCD20930835 PMID: 11799126 12502850 1518869 21277928   
Retroviridae 11632 Human immunodeficiency virus 2 11709 Homo sapiens (Human) 9606P01730 NP_000607.1CD4 moleculeCD4920 PMID: 17346169 8929542   
Retroviridae 11632 Human immunodeficiency virus 2 11709 Homo sapiens (Human) 9606P61073NP_001008540.1C-X-C motif chemokine receptor 4CXCR47852 PMID: 8929542 8929542   
Retroviridae 11632 Human immunodeficiency virus 2 11709 Homo sapiens (Human) 9606Q9NNX6 NP_001138365.1CD209 moleculeCD20930835 PMID: 12502850 1518869   
Retroviridae 11632 Simian immunodeficiency virus 11723 Pan troglodytes (Chimpanzee) 9598P16004NP_001009043.1CD4 moleculeCD4450124 PMID: 2454642   
Retroviridae 11632 Simian immunodeficiency virus 11723 Pan troglodytes (Chimpanzee) 9598P56440 NP_001009046.1C-C motif chemokine receptor 5CCR5450128 PMID: 10196302   
Retroviridae 11632 Jaagsiekte sheep retrovirus 11746 Ovis aries (Sheep) 9940Q8SQG7NP_001009754.1hyaluronoglucosaminidase 2HYAL2443154 PMID: 15596803   
Retroviridae 11632 Mouse mammary tumor virus 11757 Mus musculus (Mouse) 10090Q62351 NP_035768.1transferrin receptorTfrc22042 PMID: 18829060   
Retroviridae 11632 Baboon endogenous virus strain M7 11764 Homo sapiens (Human) 9606Q15758NP_001138616.1solute carrier family 1 member 5SLC1A56510 PMID: 10196349   
Retroviridae 11632 Feline endogenous virus RD114 11767 Homo sapiens (Human) 9606Q15758 NP_001138616.1solute carrier family 1 member 5SLC1A56510 PMID: 10051606 10196349   
Retroviridae 11632 Simian sarcoma-associated virus 11818 Homo sapiens (Human) 9606Q8WUM9NP_005406.3solute carrier family 20 member 1SLC20A16574 PMID: 8411376   
Retroviridae 11632 Xenotropic murine leukemia virus 11837 Homo sapiens (Human) 9606Q9UBH6 NP_001129141.1xenotropic and polytropic retrovirus receptor 1XPR19213 PMID: 9990033   
Retroviridae 11632 Gibbon ape leukemia virus 11840 Homo sapiens (Human) 9606Q08357NP_001244109.1solute carrier family 20 member 2SLC20A26575 PMID: 8302848   
Retroviridae 11632 Gibbon ape leukemia virus 11840 Homo sapiens (Human) 9606Q8WUM9 NP_005406.3solute carrier family 20 member 1SLC20A16574 PMID: 2078500 1309898 12097582   
Retroviridae 11632 Gibbon ape leukemia virus 11840 Cricetulus griseus (C. hamster) 10029Q9ES44NP_001230939.1solute carrier family 20 member 2SLC20A2100689023 PMID: 11000257   
Retroviridae 11632 Bovine leukemia virus 11901 Bos taurus (Bovine) 9913Q865S1 NP_776423.3adaptor related protein complex 3 delta 1 subunitAP3D1281023 PMID: 7998843   
Retroviridae 11632 Feline leukemia virus strain B/lambda-B1 103916 Homo sapiens (Human) 9606Q08357NP_001244109.1solute carrier family 20 member 2SLC20A26575 PMID: 11435563   
Retroviridae 11632 Feline leukemia virus strain B/lambda-B1 103916 Homo sapiens (Human) 9606Q8WUM9 NP_005406.3solute carrier family 20 member 1SLC20A16574 PMID: 1309898 12097582   
Retroviridae 11632 Feline leukemia virus strain B/lambda-B1 103916 Felis catus (Cat) 9685Q95L97NP_001009839.1solute carrier family 20 member 2SLC20A2493788 PMID: 11602698   
Retroviridae 11632 Feline leukemia virus strain C/FA27 103917 Homo sapiens (Human) 9606Q9Y5Y0 NP_054772.1feline leukemia virus subgroup C cellular receptor 1FLVCR128982 PMID: 10648427 10400745 20610401   
Retroviridae 11632 Feline leukemia virus strain C/FA27 103917 Felis catus (Cat) 9685Q9N1F2NP_001009302.1feline leukemia virus subgroup C cellular receptor 1FLVCR1493854 PMID: 10648427   
Retroviridae 11632 Amphotropic murine leukemia virus 188539 Homo sapiens (Human) 9606Q08357 NP_001244109.1solute carrier family 20 member 2SLC20A26575 PMID: 9151850   
Retroviridae 11632 Amphotropic murine leukemia virus 188539 Cricetulus griseus (C. hamster) 10029Q9ES44NP_001230939.1solute carrier family 20 member 2SLC20A2100689023 PMID: 9151850 8278411   
Retroviridae 11632 Amphotropic murine leukemia virus 188539 Mus musculus (Mouse) 10090Q80UP8 NP_035524.2solute carrier family 20, member 2Slc20a220516 PMID: 8041748 8278411   
Retroviridae 11632 Amphotropic murine leukemia virus 188539 Rattus norvegicus (Rat) 10116Q63488NP_058919.1solute carrier family 20 member 2Slc20a229502 PMID: 8041748 8278411   
Retroviridae 11632 Porcine endogenous retrovirus A 194958 Papio hamadryas (Baboon) 9557Q863Y8 NOsolute carrier family 52 member 2SLC52A2NO PMID: 12740431   
Retroviridae 11632 Porcine endogenous retrovirus A 194958 Homo sapiens (Human) 9606Q9HAB3NP_001240744.1solute carrier family 52 member 2SLC52A279581 PMID: 12740431 20463145   
Retroviridae 11632 Porcine endogenous retrovirus A 194958 Homo sapiens (Human) 9606Q9NWF4 NP_001098047.1solute carrier family 52 member 1SLC52A155065 PMID: 12740431 20463145   
Retroviridae 11632 Porcine endogenous retrovirus A 194958 Sus scrofa (Pig) 9823Q863Y7NP_001004033.1solute carrier family 52 member 2SLC52A2445519 PMID: 12740431   
Retroviridae 11632 Simian type D retrovirus -Tsukuba 301864 Homo sapiens (Human) 9606Q15758 NP_001138616.1solute carrier family 1 member 5SLC1A56510 PMID: 10196349   
Retroviridae 11632 Ecotropic murine leukemia virus 1511762 Mus musculus (Mouse) 10090Q09143NP_001288353.1solute carrier family 7 (cationic amino acid transporter, y+ system), member 1Slc7a111987 PMID: 2541919   
Retroviridae 11632 Polytropic murine leukemia virus 1511763 Homo sapiens (Human) 9606Q9UBH6 NP_001129141.1xenotropic and polytropic retrovirus receptor 1XPR19213 PMID: 9990033